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It has taken a while to see any effects, but that is fairly normal when you start taking supplements. I found out D-ribose was recommended for Fibromyalgia and with some scepticism I tried it. It is reducing my symptoms quite considerably.
I use D-ribose in combination with Acetyl-l-carnitine & Co-q10 to help with providing energy to the muscles which is lacking with M.E. - muscles doesn't just mean leg & arm muscles but heart, brain, lungs, eyes etc. Allows me to go to work each day.